Every great city has a soul. A human avatar that embodies their citys heart and wields its magic. New York? Shes got six.

But all is not well in the city that never sleeps. Though Brooklyn, Manny, Bronca, Venezia, Padmini, and Neek have temporarily managed to stop the Woman in White from invadingand destroying the entire universe in the processthe mysterious capital E Enemy has more subtle powers at her disposal. A new candidate for mayor wielding the populist rhetoric of gentrification, xenophobia, and law and order may have what it takes to change the very nature of New York itself and take it down from the inside. In order to defeat him, and the Enemy who holds his purse strings, the avatars will have to join together with the other Great Cities of the world in order to bring her down for good and protect their world from complete destruction.