A 45-year-old woman begins a new life in a nondescript American motel. A semi-famous artist announces her plan to drive cross-country from LA to NY. Thirty minutes after leaving her husband and child at home, she spontaneously exits the freeway, beds down in a nondescript motel and immerses herself in a temporary reinvention that turns out to be the start of an entirely different journey.

All Fours tells the story of one woman's quest for a new kind of freedom. Part absurd entertainment, part tender reinvention of the sexual, romantic and domestic life of a 45-year-old female artist, the novel excavates beliefs about life lived as a woman.